Don’t forget to apply your updates and patches! The easiest way is to setup the automatic update feature. Microsoft releases its updates/patches on Patch Tuesday which is the second Tuesday of each month, but they do issue important security patches whenever necessary throughout the month.
Just as important, don’t forget to patch other software on your computer. Believe it or not modern operating systems such as Mac OS X and Windows Vista and 7 are pretty secure so most hackers don’t try to exploit the OS directly. They instead go after a piece of software that is out of date. So make sure you patch Adobe, Java, Office, web browsers, etc.